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pentobarbital will lessen the level or outcome of nisoldipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.pentobarbital increases effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Caution/Observe. Coadministration of ifosfamide with CYP2B6 inducers may well raise metabolism of ifosfam